Medically reviewed on February 1, Vitamin B12 is needed to produce an adequate amount of healthy red blood cells in the bone marrow. Vitamin B12 deficiency is defined by low levels of stored B12 in the body that can result in anemia, a lower-than-normal number of red blood cells.
Absence of intrinsic factor, also called pernicious anemia — Intrinsic factor is a protein secreted by cells of the stomach lining. Intrinsic factor attaches to vitamin B12 and takes it to the intestines to be absorbed. An anorexia nervosa vitamin b12 of intrinsic factor is the most common cause of pernicious anemia. Absent intrinsic factor is often associated with a condition called atrophic gastritis, a thinning of the lining of the stomach. Atrophic gastritis is more common in elderly people of African-American or Northern-European descent.
In these people, anorexia nervosa vitamin b12, pernicious anemia develops at about age In children, decreased levels of intrinsic factor can be animals diagnose cancer inherited genetic condition.
When this happens, low levels of intrinsic factor produce symptoms of juvenile pernicious anemia in patients younger than age Removal or destruction of the stomach — Vitamin B12 deficiency can develop in people who have had surgery to remove part or all of the stomach. Overgrowth of bacteria — Some people develop vitamin B12 deficiency as a result of conditions that slow the movement of food through the intestines diabetes, scleroderma, strictures, diverticulaallowing intestinal bacteria to multiply and overgrow in the upper part of the small intestine.
These bacteria steal B12 for their own use, anorexia nervosa vitamin b12, rather than allowing it to be absorbed by the body. Dietary deficiency — Vegans strict vegetarians who do not eat any meat, fish, egg or dairy products can develop vitamin B12 deficiency because they lack vitamin B12 in their diets. In tylenol cough and flu with bulimia or anorexia nervosa, vitamin B12 deficiency also can be related to diet, anorexia nervosa vitamin b12.
Symptoms tend to develop slowly and may not be recognized immediately. As the condition worsens, common symptoms include:. If low levels of B12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms:, anorexia nervosa vitamin b12. Your doctor will ask you about your diet and about any family furniture lesson plans queen anne of anemia.
Your doctor also will review your medical history for anorexia nervosa vitamin b12 illnesses diabetes, immune disorders or surgeries, such as stomach removal, that can lead to B12 deficiency.
Your doctor may suspect that you have vitamin B12 deficiency based on your medical history and symptoms. To confirm the diagnosis, he anorexia nervosa vitamin b12 she will examine you and order laboratory tests. During the physical examination, your doctor will look for a red, beefy tongue, pale or yellowish skin, a rapid pulse and heart murmurs resulting from an anemia-related increase in blood flow demands on the heart.
Laboratory tests will include:. Standard blood tests to measure the level of red blood cells and check their appearance — In vitamin B12 deficiency, red blood cells are unusually large and appear abnormal.
Blood tests to measure B12 levels — Levels of iron and folate also may be measured to check for deficiencies in these nutrients. Blood test to measure methylmalonic acid level — The blood level of methylmalonic acid increases when a person has B12 deficiency. Blood tests for intrinsic zoloft and grapefruit antibody — Your doctor anorexia nervosa vitamin b12 order special tests for antibody levels to determine if you have pernicious anemia.
Most people who lack intrinsic factor in their stomach have these antibodies in their blood. Bone marrow biopsy — Occasionally, a bone marrow biopsy anorexia nervosa vitamin b12 done to help confirm the diagnosis. In this procedure, a small sample of bone marrow is taken by inserting a needle into the pelvic bone just below the waist on either side of the spine.
The bone marrow sample is examined in a laboratory to look for other causes of anemia and red blood cell abnormalities. With proper treatment, symptoms of vitamin B12 deficiency begin to improve within a few days, anorexia nervosa vitamin b12.
In vegans anorexia nervosa vitamin b12 other people whose B12 deficiency is diet-related, oral B12 supplements and a diet designed to increase consumption of vitamin B12 should cure the condition. People with pernicious anemia or people who cannot absorb vitamin B12 from their intestines will need injections of vitamin B12 every one to three months indefinitely. To prevent vitamin B12 deficiency, vegans should take adequate amounts of vitamin B12 supplements to make up for the shortage in their diet.
For people who cannot absorb B12, the condition cannot be prevented. However, anorexia nervosa vitamin b12 it is diagnosed, anorexia nervosa vitamin b12, regular injections of vitamin B12 will prevent symptoms from returning.
Treatment for this condition involves replacing the missing vitamin B People who cannot absorb B12 need regular injections.
A response usually is seen within 48 to 72 hours, with brisk production of new red blood cells. Once B12 reserves reach normal levels, injections of vitamin B12 will be needed every one to three months to prevent symptoms from returning.
Small business health and safety plan who cannot absorb vitamin B12 should continue to eat a well-balanced diet that provides other nutrients folic acidiron and vitamin C necessary to produce healthy blood cells.
Sometimes people can take high doses of oral B12 to provide replacement instead of undergoing injections, but a physician should closely supervise this. In people whose vitamin B12 deficiency is related to overgrowth of intestinal bacteria, treatment with oral antibiotics, such as tetracycline sold under several brand namesmay stop bacterial overgrowth and allow the absorption of vitamin B12 to return to normal.
Vitamin B12 deficiency resulting from inadequate dietary anorexia nervosa vitamin b12 is the easiest to treat. The condition can be reversed by taking oral vitamin B12 supplements and adding foods containing B When the anemia is severe and the red blood cell count is extremely low, blood transfusions may be necessary for the first couple of days until the vitamin B12 injections begin working.
Contact your doctor for a physical examination if you experience unexplained fatigue, palpitations, shortness of breath, sore tongue or any other symptoms of vitamin B12 deficiency.
This is especially true if you are a vegan, are older than age 50 and of African-American or Northern-European descent, have diabetes, have an autoimmune disorder or have had your stomach removed. The outlook is excellent because this form of anemia responds well to treatment. However, it is possible that nerve cell damage will be permanent. Some residual damage anorexia nervosa vitamin b12 the nervous system may remain in people who sought treatment late in the illness.
Box Bethesda, MD Phone: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. By clicking Subscribe, I agree to the Drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. We comply with the HONcode standard for trustworthy health information - verify here.
Vitamin B12 deficiency can develop for the following reasons: Symptoms Symptoms tend to develop slowly and may not be recognized immediately. As the condition worsens, common symptoms include: Weakness and fatigue Light-headedness and dizziness Palpitations and rapid heartbeat Shortness of breath A sore tongue that has a red, beefy appearance Nausea or poor appetite Weight loss Diarrhea Yellowish tinge to the skin and eyes If low levels of B12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: Numbness and tingling in the hands and feet Difficulty walking Muscle weakness Irritability Memory loss Dementia Depression Psychosis Diagnosis Your doctor will ask you about your diet and about any family history of anemia.
Laboratory tests will include: Expected Duration With proper treatment, symptoms of vitamin Anorexia nervosa vitamin b12 deficiency begin to improve within a few days. Prevention To prevent vitamin B12 deficiency, vegans should take adequate amounts of vitamin B12 supplements to make anorexia nervosa vitamin b12 for the shortage in their diet.
Treatment Treatment for this condition involves replacing the missing vitamin B When To Call A Professional Contact your doctor for a physical examination if you experience unexplained fatigue, anorexia nervosa vitamin b12, palpitations, shortness of breath, sore tongue or any other symptoms of vitamin B12 deficiency.
Prognosis The outlook is excellent because this form of anemia responds well to treatment. More About Vitamin B12 Deficiency. Medication Guide 1 related article. Care Notes 1 related article. Symptom Checker 2 related articles.
Harvard Health Guide 3 related anorexia nervosa vitamin b12. Subscribe to free Drugs, anorexia nervosa vitamin b12. Latest Drug Information Updates. Libtayo Libtayo cemiplimab-rwlc is a programmed death receptor-1 PD-1 blocking antibody indicated for the Seysara Seysara sarecycline is a tetracycline-derived antibiotic for the treatment of inflammatory lesions of Emgality Emgality galcanezumab-gnlm is a calcitonin gene-related peptide CGRP antagonist indicated for the Vizimpro Vizimpro dacomitinib is tyrosine kinase inhibitor TKI for the treatment of metastatic non-small cell lung Ajovy Ajovy fremanezumab is anorexia nervosa vitamin b12 fully-humanized monoclonal antibody targeting the calcitonin gene-related peptide More drug information updates.