Senior study author Dr. Crandall added that some people also take the drug to prevent diabetesand to treat polycystic ovarian syndrome PCOSmetformin and anemia and reversal, one of the most common causes of female infertility.
For the study, Crandall and her team looked at data from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study, which followed individuals at high risk for Type 2 diabetes for more than a decade. At the start of the study, more than 3, participants age 25 years and older had high blood sugar.
They were randomly assigned to receive either milligrams of metformin twice daily, placebo medication, or an intensive lifestyle program not metformin and anemia and reversal medication. Only those taking metformin were included in the new analysis, and about 50 participants were excluded who had undergone weight-loss surgery, which would affect their diabetes outcomes.
Researchers took blood samples from the participants at the 5- and year follow-ups. Average B12 levels were higher at the year-point than at 5 years, but B12 deficiency was also found to be more common in both the metformin and the placebo groups. At 5 years, more of the metformin patients had anemia than the placebo group, as well. The authors note that although evidence points to metformin exposure creating low B12 levels, assessment of levels in individuals treated with metformin has not been incorporated into practice guidelines.
The human body does not produce vitamin B A B12 deficiency can lead to anemiametformin and anemia and reversal, as well as cause brain and nerve damage. The vitamin metformin and anemia and reversal helps us absorb folic acid. People with low vitamin B12 levels are more likely to brain shrinkage and cognitive decline.
That said, our study and others suggests that a small but significant number of which antibiotics can cause aplastic anemia may develop deficiency.
Easy Immune System Health. Skip to main content. What do Plastic Recycling Symbols Mean? Post written by Julie Fidler: Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.