Pharmacokinetics of theophylline: a dose-range study.

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Pharmacokinetic animal studies of theophylline

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Plasma curves were fitted according to a one compartment open model. Some impairment of demethylation to 3-methylxanthine was observed in two subjects, however the percentage of theophylline and its major metabolites excreted in urine was constant for all the four doses. National Center for Biotechnology InformationU. Br J Clin Pharmacol. This article has been cited by other articles in PMC.

Abstract 1 Pharmacokinetics of theophylline were investigated in a group of healthy adult volunteers pharmacokinetic animal studies of theophylline smokers and on xanthine-free diet following single oral administration of, and mg doses as tablets Theodel, pharmacokinetic animal studies of theophylline. Kinetics of intravenous theophylline.

Effect of dietary protein and carbohydrate on theophylline metabolism in children. Effect of age on patterns of theophylline metabolism.

Effects of allopurinol on theophylline metabolism pharmacokinetic animal studies of theophylline clearance. Monitoring serum theophylline levels. Clinical experience with theophylline. Relarionships between dosage, serum concentration, and toxicity. Relationship of urinary metabolites of theophylline to serum theophylline levels. Application to adjustment of the clinical dose of aminophylline. Measurement of excretion characteristics of theophylline and its major metabolites. Eur J Clin Pharmacol.

Factors affecting theophylline clearances: Effect of charcoal-broiled beef on antipyrine and theophylline metabolism. Pharmacokinetics of sustained release theophylline in low and high multidose regimens.

Dose-dependent elimination kinetics of theophylline. Pharmacokinetic analysis of the effect of theophylline on pulmonary function in asthmatic children. Renal clearance of theophylline in man. Theophylline metabolism by the rat liver microsomal system. J Pharmacol Exp Ther. Pharmacokinetics of intravenous theophylline. Rational intravenous doses of theophylline. N Engl J Med. Influence of methylxanthine-containing foods on theophylline metabolism and kinetics, pharmacokinetic animal studies of theophylline.

Simultaneous determinations by theophylline and its major metabolites in urine by reversed-phase ion-pair high-performance liquid chromatography. Clinical pharmacokinetics of theophylline. Monitoring plasma theophylline concentrations. Total-body potassium in health: Dose-dependent kinetics for theophylline: Pharmacokinetics and metabolism of theophylline in patients with liver diseases. Evaluation of the absorption from 15 commercial theophylline products indicating deficiencies in currently applied bioavailability criteria.

Dose-dependent kinetics of theophylline disposition in asthmatic children. Support Center Support Center. Please review our privacy policy.


Pharmacokinetic animal studies of theophylline