Some abnormal tardive dyskinesia and vitamin e characteristic of TD include grimacing, sticking out the tongue, smacking and sucking of the lips, and sometimes, rapid movements of the arms and legs.
Recent evidence suggests that symptoms may begin as early as one month after beginning medications, affecting more than 1 in four older patients annually 2. Treatments are poor and involve additional medications which also have their limitations. In the B6 study of TD, fifteen patients with schizophrenia who met research criteria for tardive dyskinesia were randomly given treatment with either vitamin B6 or placebo for 4 weeks in a double blind cross over fashion.
The study found significant improvements in various movement scores i. No adverse effects were noted. It is important to mention that B6 in TD is not new. One of the first positive reports of B6 for TD was a small study published in the Journal of Clinical Psychiatry back in 3.
Responses were noticed within as little as 1 week of treatment as compared to 3 weeks in the previous study ; the high doses were well tolerated. Why has there been an over year delay with this single vitamin and TD? Supporters of nutritional medicine have reported significant benefit not only with B6, but also with additional nutrients for TD.
Kunin demonstrated dramatic results in treating TD with the mineral manganese and vitamin B3 4,5. Hawkins reported the successful prevention of TD in a total of 61, patients using vitamins B3, C and B6 6. Recommended dosages of nutrients are listed at the end of this article. Vitamin B6 is readily available, cheap, and safe. Another recent study, reported in the November issue of the Archives of General Psychiatry, examined using melatonin for TD. Along with B6 and melatonin, additional nutrients should be utilized for TD and also for its prevention.
Nutrient dosages for treatment of tardive dyskinesia:. All doses are total daily recommendations. It is best to separate in divided doses for all nutrients employed, tardive dyskinesia and vitamin e. Vitamin B3 niacin or niacinamide: Fairly mainstream vitamin for TD. Doses should not be less than IU per day and greater if it is the only nutrient employed i. Lerner V et al. Vitamin B 6 in the treatment of tardive dyskinesia: Am J Psychiatry ; 9: Jeste, DV tardive dyskinesia and vitamin e al.
Incidence of tardive dyskinesia in early stages of low-dose treatment with typical neuroleptics in older patients. Am J Psychiatry ; 2: High-dose pyridoxine in tardive dyskinesia. J Clin Psychiatry ; Manganese and niacin in the treatment of drug-induced dyskinesias, tardive dyskinesia and vitamin e. J Orthomolecular Psychiatry tardive dyskinesia and vitamin e 1: Successful prevention of tardive dyskinesia. J Orthomolecular Medicine ;4 1: Walter Lemmo, ND W.
Nutrient dosages for treatment of tardive dyskinesia: It is best to separate in divided doses for all nutrients employed Preventing TD Hawkins: Tardive dyskinesia treated with manganese.