Medically reviewed on April 11, Hoodia gordonii is a cactus-like weight loss and hoodia plant, native to the Kalahari Desert in southern Africa. Hoodia grows in clumps of upright stems with tan flowers and thorns, and a strong, unpleasant odor. Patients may not be able to take Hoodia, or may require special monitoring during treatment if they have any of the conditions or are taking any of the medicines listed above. Hoodia has not been evaluated by the FDA for safety, effectiveness, or purity.
Additionally, there are no regulated manufacturing standards in place for these compounds. Hoodia is available for purchase in retail stores and online; however, clinical trials have not proven Hoodia effectiveness or safety. Actual amounts of hoodia in weight loss and hoodia products cannot always be confirmed, and products may be counterfeit or contaminated.
Because many of these products are promoted for weight loss, but have not been clinically evaluated, weight loss and hoodia, the manufacturers are in violation of the Federal Food, Drug, and Cosmetic Act. This product may also interact in life threatening ways with other medications a consumer may be taking. The appetite suppressant effects of Hoodia were first observed in by a Dutch anthropologist studying the primitive San Bushmen of the Kalahari Desert.
It was noticed that the nomadic Bushmen, who call it Xhoba ate the stem of the Hoodia plant to stave off hunger during long hunting trips in the sparsely vegetated area.
The active ingredient in Hoodia is the appetite-suppressing molecule, P57, or oxypregnane steroidal glycoside P57AS3. It is theorized that P57 acts on the brain in a manner similar to glucose. It tricks the brain into thinking one is full even when they have not eaten, reduces interest in food and delays the time before hunger sets in.
It appears to work weight loss and hoodia the level of the hypothalamus to inhibit hunger signals. Patients should not take Hoodia without first talking to their doctor if they are pregnant or could become pregnant. Patients should not take Hoodia without first talking to their doctor if they are breast-feeding. There is no information available regarding the use of Hoodia by children. The use of Hoodia in cultural and traditional settings may differ from concepts accepted by current Western medicine.
When considering the use of herbal supplements, weight loss and hoodia, consultation with a primary health care professional is advisable. No information is weight loss and hoodia regarding a missed dose of Hoodia. Consult with a doctor, pharmacist, or health care provider if additional information is required.
There are no known restrictions on food, beverages, or activity while taking Hoodia, unless otherwise directed by a health care provider. There is limited drug interaction information available between Hoodia and other medicines. P57 exhibited weak inhibition of the liver cytochrome P 3A4 enzyme.
Published, peer-reviewed, randomized controlled clinical trials evaluating the efficacy of Hoodia gordonii are lacking. A day, randomized clinical trial published in evaluated Hoodia gordonii purified extract HgPE relative to placebo, weight loss and hoodia. Menus otherwise were unchanged and portions were not controlled. HgPE was less well-tolerated than placebo due to episodes of nausea, weight loss and hoodia, vomiting, and skin sensations.
Blood pressure, pulse, heart rate, bilirubin and alkaline phosphatase were significantly increased in the HgPE group. No significant effects on energy intakes or weight relative to placebo were demonstrated.
Always consult your healthcare provider to ensure weight loss and hoodia information displayed on this page applies to your personal circumstances. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide.
By clicking Subscribe, I agree to the Drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available tanning and naprosyn Android and iOS devices.
Subscribe to receive email notifications whenever new articles are published, weight loss and hoodia. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. We comply with the HONcode standard for trustworthy health information - verify here. Hoodia gordonii Common Names: References van Heerden FR.
Pawar RS, et al, weight loss and hoodia. In vitro metabolic stability and intestinal transport of P57AS3 P57 from Hoodia gordonii and its interaction with drug metabolizing enzymes. Bradford R, et al. Effects of d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum zoloft and trazodone intake, and body weight in healthly, overweight women: Am J Clin Nutr.
Print this page Add to My Med List. Guide to Weight Loss Drugs. Pregnancy Category Not classified. Hoodia Rating No reviews - Add your review. Subscribe to free Drugs. FDA alerts for all medications.